Algebraic Statistics for Computational Biology by L Pachter

Algebraic Statistics for Computational Biology by L Pachter

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Summary

This book, first published in 2005, explains how computational algebra provides tools for designing new algorithms for exact, accurate results in the quantitative analysis of biological sequence data. These are applied to biological problems such as aligning genomes, finding genes and constructing phylogenies.

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Algebraic Statistics for Computational Biology by L Pachter

The quantitative analysis of biological sequence data is based on methods from statistics coupled with efficient algorithms from computer science. Algebra provides a framework for unifying many of the seemingly disparate techniques used by computational biologists. This book, first published in 2005, offers an introduction to this mathematical framework and describes tools from computational algebra for designing new algorithms for exact, accurate results. These algorithms can be applied to biological problems such as aligning genomes, finding genes and constructing phylogenies. The first part of this book consists of four chapters on the themes of Statistics, Computation, Algebra and Biology, offering speedy, self-contained introductions to the emerging field of algebraic statistics and its applications to genomics. In the second part, the four themes are combined and developed to tackle real problems in computational genomics. As the first book in the exciting and dynamic area, it will be welcomed as a text for self-study or for advanced undergraduate and beginning graduate courses.
'As the first book in this exciting and dynamic area, it will be welcomed as a text for self-study or for advanced undergraduate and beginning graduate courses' L'enseignement mathematique
'… substantial, enthusiastically presented, and confidently written …' Publication of the International Statistical Institute
'This book is of great interest to research workers, teachers and students in applied statistics, biology, medicine and genetics.' Zentralblatt MATH
Lior Pachter is Associate Professor of Mathematics at the University of California, Berkeley. He received his PhD in mathematics from the Massachusetts Institute of Technology in 1999. He then moved to the mathematics department at UC Berkeley where he was a postdoctoral researcher for two years, before being hired as an assistant professor. He has been awarded an NSF Career award, and has received the Sloan Fellowship for his work on molecular biology and evolution. Equally at home amongst both mathematicians and biologists, he has published over 40 research articles in areas ranging from combinatorics to gene finding, and has participated in several large genome projects. Bernd Sturmfels is Professor of Mathematics and Computer Science at the University of California, Berkeley. His honors include a National Young Investigator Fellowship, a Sloan Fellowship, and a David and Lucile Packard Fellowship. Sturmfels served as von Neumann Professor at TU Munich in Summer 2002, as the Hewlett-Packard Research Professor at MSRI Berkeley in 2003/04, and he was a Clay Senior Scholar in 2004.
SKU Unavailable
ISBN 13 9780521857000
ISBN 10 0521857007
Title Algebraic Statistics for Computational Biology
Author L Pachter
Condition Unavailable
Binding Type Hardback
Publisher Cambridge University Press
Year published 2005-08-22
Number of pages 434
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
Note Unavailable