The Cytokines of the Immune System
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The Cytokines of the Immune System by Zlatko Dembic Md
Cytokines of the Immune System: The Role of Cytokines in Disease Related to Immune Response, Second Edition is a comprehensive and essential resource for graduate and postgraduate training of physicians, dentists, biomedical specialists, and those interested in scientific research in biology and biochemistry. The book provides an up-to-date, textbook-like description of immunology, focusing on the critical role of cytokines in immune responses. With advancements in cytokine research and signal transduction, this new and improved edition offers a deeper understanding of cytokine-receptor interactions, supported by novel figures based on crystal-structure conformations from the protein database. These insights are invaluable for inspiring new drug designs and therapeutic strategies. The book delivers a thorough overview of immunology, detailing the development and regulation of the immune system, with a special focus on cytokines. It presents an upgraded description of interleukins, immune-modulatory cytokines, and chemokines, exploring their structure, sources, functions, receptors, disease associations, and therapeutic potentials. This edition also introduces the latest information on innate lymphoid cells and their cytokines, as well as their adaptive immunity counterparts. A dedicated chapter on the cytokine storm provides critical insights into this phenomenon.
Dr. Zlatko Dembic, a distinguished scientist and medical doctor, has dedicated his career to exploring the intersections of medicine and biology, particularly in molecular and cellular immunology. Over the last two decades of the 20th century, he worked at prestigious institutions such as the Max-Planck-Institute for Biology in Germany, the Basel Institute for Immunology in Switzerland, and Hoffman-La Roche AG. His team was the first to identify genes underlying T-cell specificity and recognition, and they led the molecular cloning of key human cytokine receptors like the interferon-gamma receptor and the tumor necrosis factor receptor-2. In 1995, Dr. Dembic joined the Institute of Immunology at the University of Oslo, expanding his research to include T-cell development, cancer immunobiology, and immunogenetics. He proposed the "integrity" model of the immune system, emphasizing immunity's role in defense and symbiont selection and has over 100 scientific publications in many high impact factor scientific journals.
| SKU | Unavailable |
| ISBN 13 | 9780443451287 |
| ISBN 10 | 0443451281 |
| Title | The Cytokines of the Immune System |
| Author | Zlatko Dembic Md |
| Condition | Unavailable |
| Binding Type | Paperback |
| Publisher | Elsevier Science Publishing Co Inc |
| Year published | 2026-07-01 |
| Number of pages | 325 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
| Note | Unavailable |