Drawings of William Blake by William Blake

Drawings of William Blake by William Blake

The growing knowledge on tumor-immune response interactions and on the tumor microenvironment did not translate so far into better control of cancer by anti-tumor vaccination. The percentage of patients who benefited from vaccination strategies is still too small to justify their general use. It is the aim of this book to present an alternative to the conventional approach of developing injected tumor vaccines to activate anti-tumor immunity, which will fight cancer. It is argued that in situ tumor ablation (destruction) that involves tumor antigen release; cross presentation and the release of danger associated molecular patterns (DAMPs) can make the tumor its own cellular vaccine.

Tumor ablation methods using chemicals, radiation, photodynamic therapy, cryoablation, high-temperature, radiofrequency, high intensity focused ultrasound, and electric-based ablation have been developed for focal tumors. In this book experts will deal with two main topics: I. What are the principles of the various ablation modalities, and I. How each method affects the tumor cells and their microenvironment, and how these effects are responsible for the induction of specific anti-tumor immunity.

The aims of this book are thus: 1. Familiarize the readers with various methods of in situ tumor ablation. 2. Review the literature and stimulate comparisons on the efficacy of different ablation methods for the treatment of tumors of different histotypes. 3. Review the literature on the effects of various ablation methods on systemic and local anti tumor immunity and on other manifestations of the interactions of tumors with their microenvironment. 4. Stimulate comparative studies on the immunostimulatory effects of different ablation modalities.

WILLIAM BLAKE was born in London in 1757. He was educated at home and then worked as an apprentice to the engraver James Basire before joining the Royal Academy in 1779. In 1782 he married Catherine Boucher, and a year later began his career as a poet when he published Poetical Sketches. This was followed by Songs of Innocence (1789) and Songs of Experience (1794), which he also designed and engraved. His other major literary works include The Book of Thel (1789), The Marriage of Heaven and Hell (c. 1793), Milton (1804-8), and Jerusalem (1804-20). He produced many paintings and engravings during his lifetime. Blake died in 1827.

ALFRED KAZIN was born in Brooklyn in 1915. His first book of criticism, On Native Grounds (1942), was a groundbreaking study of American literature that changed radically our way of looking at it, and established him overnight as a major figure. In a series of books of his own since then, and in many critically edited texts of classic American literary works, he established himself as our preeminent man of letters. He taught widely at Harvard, Smith, Amherst, Hunter College, the Graduate Center of the City University of New York, and elsewhere. In 1996 he received from the Truman Capote Literary Trust its first Lifetime Achievement Award in Literary Criticism (in memory of Newton Arvin). He died in 1998.

SKU	Unavailable
ISBN 13	9780486223032
ISBN 10	0486223035
Title	Drawings of William Blake
Author	William Blake
Series	Dover Fine Art History Of Art
Condition	Unavailable
Publisher	Dover Publications Inc.
Year published	2012-03-14
Number of pages	192
Cover note	Book picture is for illustrative purposes only, actual binding, cover or edition may vary.