Gene Therapy: Therapeutic Mechanisms and Strategies by Sylvester Noble

Gene Therapy: Therapeutic Mechanisms and Strategies by Sylvester Noble

Gene therapy is a therapeutic technique in which nucleic acid is delivered into the cells of a patient as a drug to treat disease. The fundamental strategy in gene therapy is the use of DNA which when administered, reaches the damaged cells, enters the cell, and disrupts or expresses a protein. Multiple delivery techniques can be used for DNA delivery. Recent advances in the understanding of nuclease function have enabled direct DNA editing using CRISPR and zinc finger nucleases. Genes are incorporated into chromosomes with the help of vectors, which then express the nucleases that knock out and replace the genes in the chromosome. The vectors used in gene therapy can be recombinant viruses or naked DNA or DNA complexes. There is thus a great potential in using gene therapy and gene editing in treating genetic and viral diseases as well as cancer. The ever growing need of advanced diagnostic and therapeutic technology is the reason that has fueled the research in the field of gene therapy in recent times. The various studies that are constantly contributing towards advancing therapeutic strategies and mechanisms, and evolution of gene therapy are examined in detail. This book aims to serve as a resource guide for students and experts alike and contribute to the growth of the discipline.

SKU	Unavailable
ISBN 13	9781632418470
ISBN 10	1632418479
Title	Gene Therapy: Therapeutic Mechanisms and Strategies
Author	Sylvester Noble
Condition	Unavailable
Binding Type	Hardback
Publisher	Hayle Medical
Year published	2020-09-15
Number of pages	240
Cover note	Book picture is for illustrative purposes only, actual binding, cover or edition may vary.