Genome by Matt Ridley

Genome by Matt Ridley

The human genome, the complete set of genes housed in twenty-three pairs of chromosomes, is nothing less than an autobiography of our species. Spelled out in a billion three-letter words using the four-letter alphabet of DNA, the genome has been edited, abridged, altered and added to as it has been handed down, generation to generation, over more than three billion years. With the first draft of the human genome due to be published in 2000, we, this lucky generation, are the first beings who are able to read this extraordinary book and to gain hitherto unimaginable insights into what it means to be alive, to be human, to be conscious or to be ill.

By picking one newly discovered gene from each of the twenty-three human chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. He finds genes that we share with bacteria, genes that distinguish us from chimpanzees, genes that can condemn us to cruel diseases, genes that may influence our intelligence, genes that enable us to use grammatical language, genes that guide the development of our bodies and our brains, genes that allow us to remember, genes that exhibit the strange alchemy of nature and nurture, genes that parasitise us for their own selfish ends, genes that battle with one another and genes that record the history of human migrations. From Huntington's disease to cancer, he explores the applications of genetics: the search for understanding and therapy, the horrors of eugenics and the philosophical implications for understanding the paradox of free will.

Matt Ridley is the author of books that have sold well over a million copies in 32 languages: THE RED QUEEN, THE ORIGINS OF VIRTUE, GENOME, NATURE VIA NURTURE, FRANCIS CRICK, THE RATIONAL OPTIMIST, THE EVOLUTION OF EVERYTHING, and HOW INNOVATION WORKS. In his bestseller GENOME and in his biography of Francis Crick, he showed an ability to translate the details of genomic discoveries into understandable and exciting stories. During the current pandemic, he has written essays for the Wall Street Journal and The Spectator about the origin and genomics of the virus. His most recent WSJ piece appeared on January 16, 2021. He is a member of the House of Lords in the UK.