Isothermal Titration Calorimetry in Enzymology by Anthony Mittermaier
Isothermal Titration Calorimetry in Enzymology: Techniques and Applications provides a thorough, practical overview of ITC as a productive and powerful tool for quantifying enzyme catalysis and interactions with substrates, products, cofactors, and inhibitors. Here, global experts in the methodology discuss the full capabilities of ITC and how it may be applied in research, medicine, and industry and offer a basis to continue leveraging ITC as its uses expand and evolve. This book bridges the gap between research and application by giving extensive technical details on cutting edge ITC techniques across a wide swath of both ITC kinetics measurements and ITC thermodynamic measurements, alongside case studies illustrating the depth of knowledge that can be obtained. Applications discussed include measuring binding kinetics by ITC, analyzing ITC kinetic data, in vivo enzyme kinetics by ITC, analyzing enzyme kinetics in crowded solutions, studying catalysis of biological substrates, interpreting ITC binding curves, ITC in drug discovery, ITC in the development of cancer therapeutics, ITC analysis of aminoglycoside resistance enzymes, studying enzyme interactions with toxic metals, using ITC to study ubiquitination, and ITC studies of glycoside hydrolases, among others.- Plant Peptides
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Carrier-Free Enzyme Immobilization
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Lipases
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Bacterial Enzymes as Targets for Drug Discovery
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Super-Resolution Nanoscopy for Protein Imaging
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RNases in Health and Diseases
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Proteolytic Enzymes and their Inhibitors in Infectious Pathogens
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Cryptic Enzymes and Moonlighting Proteins
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Whole Cell Biocatalysis
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Enzymatic Production of Oligosaccharides
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Sustainable Process Intensification for Biocatalysis
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Ureases
Professor Anthony Mittermaier works in the Department of Chemistry, McGill University, Montreal, Canada. Justin Di Trani is an Assistant Professor at the University of Alberta, Department of Biochemistry, Edmonton, Canada
| SKU | Unavailable |
| ISBN 13 | 9780443218484 |
| Title | Isothermal Titration Calorimetry in Enzymology |
| Author | Anthony Mittermaier |
| Series | Foundations And Frontiers In Enzymology |
| Condition | Unavailable |
| Binding Type | Paperback |
| Publisher | Elsevier Science Publishing Co Inc |
| Year published | 2025-11-01 |
| Number of pages | 472 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
| Note | Unavailable |