Lymphoma by Tim Illidge

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Summary

Among the highlights are methods to use immunoglobulin gene rearrangements as markers of clonality, to exploit patterns of somatic mutation in the variable regions to indicate at which stage transformation occurred, and to apply gene arrays to the question of biological heterogeneity in morphologically similar diseases.

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Lymphoma by Tim Illidge

A cutting-edge collection of readily reproducible molecular techniques to better understand, classify, and treat lymphoma. Among the highlights are methods to use immunoglobulin gene rearrangements as markers of clonality, to exploit patterns of somatic mutation in the variable regions to indicate at which stage transformation occurred, and to apply gene arrays to the question of biological heterogeneity in morphologically similar diseases. Research methodologies that are highly likely to become routine practice in the future, such as DNA microarray and immunoglobulin V-gene rearrangements, and measurement of minimal disease, are included. There are also molecular techniques for providing for producing novel therapeutics, such as a DNA vaccine with patient-specific sequences derived from the lymphoma in question.
"Offers(s) a diverse collection of readily reproducible techniques for the molecular diagnosis and prognostic evaluation of lymphomas.." - Clinical Laboratory International
SKU Unavailable
ISBN 13 9781588291592
ISBN 10 1588291596
Title Lymphoma
Author Tim Illidge
Series Methods In Molecular Medicine
Condition Unavailable
Binding Type Hardback
Publisher Humana Press Inc.
Year published 2005-05-17
Number of pages 342
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.