Molecular Chaperones in Human Disorders by Rossen Donev
Molecular Chaperones in Human Disorders, Volume 114 in the Advances in Protein Chemistry and Structural Biology series, provides an overview of current developments in mechanisms underlying DNA repair and their involvement in maintaining chromatin repair, the balance between chromosomal repair pathways, tumorigenesis, immune signaling and infection-induced inflammation. Chapters in this new release cover Functional principles and regulation of molecular chaperones, Chaperones and retinal disorders, Protein misfolding and degradation in genetic diseases, Chaperone dysfunction in hereditary myopathic diseases, Diseases caused by functional disorder of molecular chaperones residing in the endoplasmic reticulum, and many other timely topics.- Proteomics and Metabolomics in Drug Discovery
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Nuclear Proteins
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Inflammation in Neuropsychiatric Disorders
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DNA Repair
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Regulation of Downstream Targets
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Structural and Mechanistic Enzymology
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Enzymes Mechanisms, Dynamics and Inhibition
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Protein Interactions as Targets in Drug Discovery
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Metalloproteins and Motor Proteins
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Control of Cell Cycle and Cell Proliferation
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Computational Chemistry Methods in Structural Biology
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Proteomics and Systems Biology
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Protein Misfolding
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Inflammatory Disorders - Part B
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Intracellular Signalling Proteins
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Protein and Peptide Nanoparticles for Drug Delivery
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Protein Interaction Networks
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Ion Channels as Therapeutic Targets, Part A
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Advances in Protein Chemistry and Structural Biology
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Combined Quantum Mechanical and Molecular Mechanical Modelling of Biomolecular Interactions
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Personalized Medicine
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Peptide and Protein Vaccines
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Inflammatory Disorders - Part A
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Apoptosis in Health and Disease - Part B
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Apoptosis in Health and Disease - Part A
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Non-heme Iron Enzymes: Structures and Mechanisms
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Protein Design and Structure
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Stress and Inflammation in Disorders
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Chromatin Remodelling and Immunity
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Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods
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Transport Proteins
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Ion Channels as Therapeutic Targets, Part B
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Protein Kinases in Drug Discovery
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Protein Misfolding Diseases
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Protein Structure Prediction and Analysis
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Immunotherapy: Magic Bullet to Change the Future Therapeutics
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Protein Aggregation - Part B
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Secretory Proteins
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Protien Aggregation - Part A
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Senescence, Senotherapeutics and Mitochondria
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Immunology for Engineers
Rossen Donev received his PhD degree in 1999 from the Institute of Molecular Biology, Bulgarian Academy of Sciences. He did postdoctoral training at Imperial Cancer Research Fund, UK (renamed after the merger with Cancer Research Campaign to Cancer Research UK, London Research Institute) and Cardiff University. In 2007 he was awarded a New Investigator Grant Award from the Medical Research Council (UK) to establish himself as an independent Principle Investigator. In 2010 Dr. Donev was appointed Senior Lecturer at Swansea University. In 2016 Dr. Donev joined MicroPharm Ltd (UK) where currently he is Head of Research. He has published more than 60 research papers, chaired scientific meetings and given invited plenary talks. Rossen Donev has consulted on projects related to development of treatments for neurodevelopmental disorders and cancer therapies. He serves as Editor-in-Chief of the Advances in Protein Chemistry and Structural Biology and on editorial board of several other journals. His research interests include signaling pathways involved in neuropsychiatric disorders and tumor escape from the immune system, and development of therapeutic strategies for their treatment. More recently he has focused on development of immunotherapeutics for non-systemic applications.
| SKU | Unavailable |
| ISBN 13 | 9780128155578 |
| ISBN 10 | 0128155574 |
| Title | Molecular Chaperones in Human Disorders |
| Author | Rossen Donev |
| Series | Advances In Protein Chemistry And Structural Biology |
| Condition | Unavailable |
| Binding Type | Hardback |
| Publisher | Elsevier Science Publishing Co Inc |
| Year published | 2019-01-09 |
| Number of pages | 423 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
| Note | Unavailable |