Sickle Cell Disease by Graham R Serjeant

Sickle Cell Disease by Graham R Serjeant

Sickle cell disease was one of the first diseases to be explained at the molecular level. Nevertheless, in the years since the first edition of this book was published, further advances have been made. Much has been learnt about the causes of variability in the natural history of the disease and of the reasons why there are such marked variations in the patterns of morbidity and mortality. The role and importance of genetic modifiers such as alpha-thalassaemia and persisting high levels of fetal haemoglobin, and of the beta-globin haplotype, have been recognized and explored. Studies of the disease which compare geographically separated populations have contributed to understanding this variability. These findings have led to more rigorous thinking about the nature of the disease and a clearer appreciation of how to manage it. This book is intended for professionals: physicians - especially haematologists, medical geneticists, paediatricians, nurses in specialist centres, health planners.

SKU	Unavailable
ISBN 13	9780192622310
ISBN 10	0192622315
Title	Sickle Cell Disease
Author	Graham R Serjeant
Condition	Unavailable
Binding Type	Paperback
Publisher	Oxford University Press
Year published	1992-09-01
Number of pages	650
Cover note	Book picture is for illustrative purposes only, actual binding, cover or edition may vary.