Viral Vectors for Gene Therapy by Fredric P Manfredsson

Viral Vectors for Gene Therapy by Fredric P Manfredsson

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Viral Vectors for Gene Therapy by Fredric P Manfredsson

This volume discusses protocols, ranging from vector production to delivery methods, used to execute gene therapy applications. Chapters are divided into four parts, and cover topics such as design, construction, and application of transcription activation-like effectors; multi-modal production of adeno-associated virus; construction of oncolytic herpes simplex virus; AAV-mediated gene delivery to the mouse liver; and intrathecal delivery of gene therapeutics by direct lumbar puncture in mice. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Viral Vectors for Gene Therapy: Methods and Protocols is a valuable resource for researchers, clinicians, and students looking to utilize viral vectors in gene therapy experiments.
SKU Unavailable
ISBN 13 9781493990641
ISBN 10 1493990640
Title Viral Vectors for Gene Therapy
Author Fredric P Manfredsson
Series Methods In Molecular Biology
Condition Unavailable
Binding Type Hardback
Publisher Humana Press Inc.
Year published 2019-02-01
Number of pages 328
Cover note Book picture is for illustrative purposes only, actual binding, cover or edition may vary.