There have been many advances in the pharmacology of pain, both in terms of mechanisms of transmission and events un-derlying the production of analgesia. This volume provides an overview of the field covering the basic science of pain and its applications. The chapters range from the peripheral events through to central mechanisms, with emphasis on the transmitters and receptors implicated in transmission and control. The book covers acute, inflammatory and neuropathic pain states and each chapter links the basic aspects with the therapeutic applications, both in terms of drug development and clinical approaches.