Section I: Cellular Physiology 1 Bruce M. Koeppen and Bruce A. Stanton 1. Principles of Cell Function 3 2. Homeostasis of Body Fluids 20 3. Signal Transduction, Membrane Receptors, Second Messengers, and Regulation of Gene Expression 34 Section II: The Nervous System 51 Kalman Rubinson and Eric J. Lang 4. The Nervous System: Introduction to Cells and Systems 53 5. Generation and Conduction of Action Potentials 65 6. Synaptic Transmission 82 7. The Somatosensory System 105 8. The Special Senses 123 9. Organization of Motor Function 157 10. Higher Functions of the Nervous System 201 11. The Autonomic Nervous System and its Central Control 218 Section III: Muscle 231 James M. Watras 12. Skeletal Muscle Physiology 233 13. Cardiac Muscle 256 14. Smooth Muscle 268 Section IV: The Cardiovascular System 287 Achilles J. Pappano 15. Overview of Circulation 289 16. Elements of Cardiac Function 292 17. Properties of the Vasculature 330 18. Regulation of the Heart and Vasculature 370 19. Integrated Control of the Cardiovascular System 393 Section V: The Respiratory System 415 Michelle M. Cloutier and Roger S. Thrall 20. Structure and Function of the Respiratory System 417 21. Mechanical Properties of the Lung and Chest Wall: Static and Dynamic 430 22. Ventilation (V), Perfusion (Q), and V/Q Relationships 444 23. Oxygen and Carbon Dioxide Transport 459 24. Control of Respiration 468 25. Nonrespiratory Functions of the Lung 477 Section VI: Gastrointestinal Physiology 485 Kim E. Barrett and Helen E. Raybould 26. Functional Anatomy and General Principles of Regulation in the Gastrointestinal Tract 487 27. The Cephalic, Oral, and Esophageal Phases of the Integrated Response to a Meal 496 28. The Gastric Phase of the Integrated Response to a Meal 504 29. The Small Intestinal Phase of the Integrated Response to a Meal 516 30. The Colonic Phase of the Integrated Response to a Meal 533 31. Transport and Metabolic Functions of the Liver 542 Section VII: The Renal System 555 Bruce A. Stanton and Bruce M. Koeppen 32. Elements of Renal Function 557 33. Solute and Water Transport along the Nephron: Tubular Function 578 34. Control of Body Fluid Osmolality and Volume 594 35. Potassium, Calcium, and Phosphate Homeostasis 619 36. Role of the Kidneys in the Regulation of Acid-Base Balance 636 Section VIII: The Endocrine and Reproductive Systems 651 Bruce A. White 37. Introduction to the Endocrine System 653 38. Hormonal Regulation of Energy Metabolism 664 39. Hormonal Regulation of Calcium and Phosphate Metabolism 696 40. The Hypothalamus and Pituitary Gland 706 41. The Thyroid Gland 725 42. The Adrenal Glands 738 43. The Male and Female Reproductive Systems 758 Index 799
