In Panama in Black, Kaysha Corinealdi traces the multigenerational activism of Afro-Caribbean Panamanians as they forged diasporic communities in Panama and the United States throughout the twentieth century. Drawing on a rich array of sources including speeches, yearbooks, photographs, government reports, radio broadcasts, newspaper editorials, and oral histories, Corinealdi presents the Panamanian isthmus as a crucial site in the making of an Afro-diasporic world that linked cities and towns like Colon, Kingston, Panama City, Brooklyn, Bridgetown, and La Boca. In Panama, Afro-Caribbean Panamanians created a diasporic worldview of the Caribbean that privileged the potential of Black innovation. Corinealdi maps this innovation by examining the longest-running Black newspaper in Central America, the rise of civic associations created to counter policies that stripped Afro-Caribbean Panamanians of citizenship, the creation of scholarship-granting organizations that supported the education of Black students, and the emergence of national conferences and organizations that linked anti-imperialism and Black liberation. By showing how Afro-Caribbean Panamanians used these methods to navigate anti-Blackness, xenophobia, and white supremacy, Corinealdi offers a new mode of understanding activism, community, and diaspora formation.