A twisted tale of sadistic Sorcerers and the monsters they create.

In a city so dismal it's known only as the Hole, a clan of Sorcerers has been plucking people off the streets to use as guinea pigs for atrocious experiments in the black arts. In a dark alley, Nikaido found Caiman, a man with a reptile head and a bad case of amnesia. To undo the spell, they're hunting and killing the Sorcerers in the Hole, hoping that eventually they'll kill the right one. But when En, the head Sorcerer, gets word of a lizard-man slaughtering his people, he sends a crew of cleaners into the Hole, igniting a war between two worlds.

As the Family continues its desperate effort to resurrect En, the worlds of the sorcerers and the Hole descend into total chaos. Can the hapless citizens of the Hole be saved? More to the point, can Caiman save Nikaido? The drama and action ramp up to a gloriously bloody climax in this final volume of the Dorohedoro series!