The Doctrine of DNA by Richard C. Lewontin
This book, the latest in the continuing debate between the genetic reductionists (such as Richard Dawkins, John Maynard Smith and E.O. Wilson) and those who argue for a rather more complex relationship between genes and the environment (such as Stephen Jay Gould, Steven Rose and Niles Eldredge). Lewontin is a forceful writer and this is an effective statement of the case against the "selfish gene".