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Vinay Kumar, MBBS, MD, FRCPath, Alice Hogge and Arthur A. Baer Distinguished Service Professor of Pathology, Biological Sciences Division and The Pritzker Medical School, University of Chicago, Chicago, Illinois Abul K. Abbas, MBBS, Distinguished Professor and Chair, Department of Pathology, University of California San Francisco, San Francisco, California Jon C. Aster, MD, PhD, Professor of Pathology, Harvard Medical School; Brigham and Women's Hospital, Boston, Massachusetts