The Dynamic Bacterial Genome by Peter Mullany
This book provides an in-depth analysis of the mechanisms and biological consequences of genome rearrangements in bacteria. Genome rearrangements are a result of the actions of discrete genetic elements such as conjugative transposons, plasmids, phage, and non-conjugative transposons. Bacteria also contain systems to mediate genetic rearrangements such as the general recombination pathway and specialized endogenous recombination mechanisms. The biological effects of these rearrangements are far-reaching and impact on bacterial virulence, antibiotic resistance and the ability of bacteria to avoid the attentions of the host immune system (e.g. antigenic variation). These rearrangements also provide the raw material on which natural selection can act. Each chapter examines the mechanisms involved in genome rearrangements and the direct biological consequences of these events. This book is written by leading research workers and is an invaluable resource for graduate students and researchers in this field.-
Horizontal Gene Transfer in the Evolution of Pathogenesis
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Bacterial Evasion of Host Immune Responses
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Phagocytosis of Bacteria and Bacterial Pathogenicity
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Salmonella Infections
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Dormancy and Low Growth States in Microbial Disease
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Bacterial Invasion of Host Cells
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Bacterial Adhesion to Host Tissues
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Susceptibility to Infectious Diseases
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Bacterial Cell-to-Cell Communication
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Bacterial-Epithelial Cell Cross-Talk
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The Influence of Cooperative Bacteria on Animal Host Biology
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Mammalian Host Defense Peptides
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Dendritic Cell Interactions with Bacteria
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Bacterial Protein Toxins
Review of the hardback: 'The book is well structured, thorough and thoughtful, and a rich source of information about the amazing dynamics of bacterial genomes' Microbiology Today
Peter Mullany is a Reader in Molecular Microbiology at University College London. His main research interests are the molecular biology and molecular ecology of conjugative transposons. He has been at the forefront of this work for the past 10 years and has pioneered the genetic analysis of the important human pathogen Clostridium difficile.
| SKU | Unavailable |
| ISBN 13 | 9780521129619 |
| ISBN 10 | 0521129613 |
| Title | The Dynamic Bacterial Genome |
| Author | Peter Mullany |
| Series | Advances In Molecular And Cellular Microbiology |
| Condition | Unavailable |
| Binding Type | Paperback |
| Publisher | Cambridge University Press |
| Year published | 2010-02-04 |
| Number of pages | 444 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
| Note | Unavailable |