Mammalian Host Defense Peptides by Deirdre A Devine
Cationic antimicrobial peptides are multifunctional peptides of the innate immune system, which not only act directly against microorganisms, but also signal between early and late immune responses and modulate inflammatory reposnes. The significance of these host defence peptides in combating infection and in host-microbe homeostasis has become increasingly clear, through advances made by microbiologists, biochemists, biophysicists, immunologists, molecular biologists, and a range of medical and pharmaceutical researchers. This book, drawing together contributions from leading scientists, reviews significant recent advances in our knowledge of mammalian antimicrobial peptides. In addition to providing up-to-date overviews of their structure, expression and biology, their multiple activities and interactions with microbial populations as well as their potential application as novel therapeutic agents are summarized. Chapters describing developments using animal models and investigations of the roles of these host defence peptides in microbial infections are complemented by chapters addressing their mechanisms of action and of microbial resistance.-
Horizontal Gene Transfer in the Evolution of Pathogenesis
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Bacterial Evasion of Host Immune Responses
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Phagocytosis of Bacteria and Bacterial Pathogenicity
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Salmonella Infections
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Dormancy and Low Growth States in Microbial Disease
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Bacterial Invasion of Host Cells
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Bacterial Adhesion to Host Tissues
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Susceptibility to Infectious Diseases
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The Dynamic Bacterial Genome
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Bacterial Cell-to-Cell Communication
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Bacterial-Epithelial Cell Cross-Talk
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The Influence of Cooperative Bacteria on Animal Host Biology
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Dendritic Cell Interactions with Bacteria
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Bacterial Protein Toxins
| SKU | Unavailable |
| ISBN 13 | 9780521822206 |
| ISBN 10 | 0521822203 |
| Title | Mammalian Host Defense Peptides |
| Author | Deirdre A Devine |
| Series | Advances In Molecular And Cellular Microbiology |
| Condition | Unavailable |
| Binding Type | Hardback |
| Publisher | Cambridge University Press |
| Year published | 2004-09-20 |
| Number of pages | 408 |
| Cover note | Book picture is for illustrative purposes only, actual binding, cover or edition may vary. |
| Note | Unavailable |